Six people were reported injured and pictures show substantial damage to the starboard wing and engine.
Six of the 128 people aboard the plane, including crewmembers, were injured in the crash, the minister of public infrastructure, David Patterson, said as cited by local media.
All Canadian passengers aboard a Toronto-bound flight with a mechanical problem escaped injury when their plane skidded off the runway at Guyana's main global airport, federal officials said Friday.
He said the injuries were not life-threatening and the wounded were taken to a hospital near the airport in this country bordering Venezuela to the east.
A Toronto-bound Fly Jamaica airplane is seen after crash-landing at the Cheddi Jagan International Airport in Georgetown, Guyana on November 9, 2018. "There were no reports of broken bones", Patterson told a news briefing at the airport.
The pilot reportedly claimed he started to experience technical issues with the hydraulics about 20 minutes into their flight and it forced him to turn around to its departure airport, according to Mr Patterson. A Boeing 737 MAX 8 operated by Lion Air crashed into the sea soon after take-off on 29 October, killing all on board.
In a statement early Friday, the airline said it believes all 120 passengers and eight crew were safe following the crash in Georgetown.
On June 30, 2011, a Caribbean Airlines plane overshot the runway at Timehri and crash-landed.
It said Flight OJ256 "suffered an accident on landing", but had no other details on the nature of the accident. A spokesman said consular assistance would be available to those who needed it.
The 118 passengers on board the Boeing 757-200 included 82 Canadians.