"This is awesome. I've been waiting my whole life for this", Mr Clarke said.
For now, cannabis can only be purchased through the government-run online portal, and Fedeli noted that any orders placed through the site would not yet have been delivered.
"I started working in this industry eight and a half years ago when there were 15 countries that had legal access to medical cannabis, today there are 35", Kennedy said.
The products are displayed in plastic or cardboard packages behind counters. Traded on the Nasdaq, it's the only cannabis company without a Canadian listing and also has a very small public float, two factors that have been blamed for recent volatility in the stock.
"'I don't need to be a criminal anymore, and that's a great feeling", said MacIsaac, who had been arrested for possession in 2001. "And my new dealer is the prime minister!" Quebec's new government has vowed to raise it further, to 21.
Each item comes with a government seal - the word cannabis above a red Maple leaf - and people can also make their purchases online, or at more than 100 stories the Associated Press reported would be open across the country.
Canada has invested C$274 million to enforce new laws and some provinces have allocated their own funding, but Palmer said police will not crack down on illegal stores right away.
In most other provinces, it will be legal to buy cannabis at 18 or 19 years old.
In the meantime, Toronto Police still intend to crack down on illegal dispensaries, with the Ontario government deeming physical stores selling weed to be afoul of the law until April.
Day One of recreational cannabis sales in Canada saw strong demand and short supplies as products quickly sold out on provincial websites and at some stores.
British Columbia, which plans both province-run and private outlets, has only one government store 350 kilometres (220 miles) from its biggest city, Vancouver.
That's why he got in line at 3:45am to buy recreational cannabis - legally.
A man rolls a marijuana cigarette during a legalization party at Trinity Bellwoods Park in Toronto.
U.S. Customs and Border Protection (CBP) released a statement late last month, clarifying its policies regarding "Canada's Legalization of Marijuana and Crossing the Border". Peterson took out a full page ad in the Wall Street Journal this week urging President Donald Trump to help ease prohibition and eliminate hurdles for the USA pot industry before Canada leaves it even farther behind.
As Canada welcomes legalization, supply shortages could develop, as happened in some USA states when legalization arrived. Kamloops City Council voted on the store opening during a meeting yesterday, with a unanimous vote and mayor Ken Christian declaring history had been made. She doesn't expect to make much money off the pot itself, noting Newfoundland's 8 percent cap on retail pot profits.
"That's not really in the spirit of legalization", Larsen said. By mid-afternoon some products were sold out. "That's not even paying someone's salary". Tracey Lindeman reported from Montreal.