L.A. still owns two more prime-time games, highlighted by a Week 11 showdown with the Chiefs in Mexico City.
NBC's Sunday Night Football picked the game up after both teams had an impressive first quarter to the 2018 season.
The Oct. 21 game against the Cincinnati Bengals at Arrowhead Stadium was originally scheduled for noon, but word came on Tuesday that it had been moved to "Sunday Night Football" at the expense of the Rams-49ers contest.
There's an obvious draw to getting the undefeated Chiefs and quarterback Patrick Mahomes on primetime, and the Bengals now sit at 4-1 and boast a talented offense of their own. The game was initially scheduled for a 1 p.m. ET kick in K.C. They take on the New England Patriots this Sunday at 7:20 p.m.
The Rams are arguably the most exciting and entertaining team in the NFL right now, but not even their high-flying offense can make up for the lack of national interest in San Francisco.
The Chiefs beat the Broncos 27-23 in a Monday night game October 1.