The drama started when Ramos handed Williams a coaching violation early in the second set because of hand gestures made from the stands by her coach Patrick Mouratoglou.
Williams, who has since been fined $17,000 by the United States Tennis Association for the violations, vigorously disputed each of them during the match.
The Sunday Project host sat down in NY with Williams for an in-depth chat that will air on tonight's episode of the Network Ten panel show - and it was a question about Williams' infamous U.S. Open meltdown that saw things get "sticky", as Wilkinson put it.
The 23-time Grand Slam champion lost in straight sets to Naomi Osaka, who became the first Japanese to win a Major singles title, after a fiery confrontation with chair umpire Carlos Ramos that she later blamed on "sexism".
Following the accusation of coaching, Williams was punished for racquet smashing and verbal abuse, following several outbursts that saw her call the umpire a "liar" and "thief".
Along with a slew of tone-deaf articles and the recent news of a potential umpire boycott of Williams' matches by the International Tennis Federation (ITF), we are reminded that, no matter how much success a black woman achieves, she will always be made to feel unwelcome or subject to excessive criticism.
I requested him: there are not any clues there. She doesn't even know to give kisses, and she just grabbed me, and I was like this little baby is so smart. Lest we forget, Williams was vying to tie Margaret McCourt's 24 Grand Slam record that night, one year after a near death experience postpartum, so the stakes were very high.
"I felt like we were literally watching history", Williams said about Markle and Prince Harry's nuptials. "As a woman you should be able to do half of what a man can", she said.
"Sascha was coaching every point too", Mouratoglou added. Given how big of a moment that was, how big of a match that was, I think it was amplified. You stole a point from me. "I think there will be some feelings there when you go onto the court".
Williams said she wanted to move on from the controversy.
'You know, I was, like, Oh, okay.
"I'm just trying most of all to recover from that and just move on", the tennis star said.
"I was on the other side, I didn't see the motion, so it was just a really confusing moment", she said.
Following the interview, Wilkinson revealed to her co-hosts that she was told to steer clear of asking the US star about Mark Knight's controversial cartoon published in the wake of the US Open.