Lloris, who has endured a hard few weeks on a personal level after being fined £50,000 and receiving a 20-month driving ban following his pleading guilty to drink-driving, misses this weekend's game with a hamstring injury, while Alli suffered a knock during England's 2-1 defeat to Spain last weekend and misses out.
Tottenham Hotspur suffered a double injury blow ahead of a key week with goalkeeper Hugo Lloris and midfielder Dele Alli ruled out for Saturday's (Sep 15) Premier League clash with Liverpool and a Champions League trip to Inter Milan on Tuesday.
Hugo Lloris will remain Tottenham captain, despite being sentenced for drink-driving this week.
"He's the first that regrets everything, and all that happened yesterday is not good", he said. "He said he is sorry and he is a man and accepts his mistake". "We are not God, we can't judge people. That is a massive lesson for everyone, he was the first to tell me he made a mistake".
He veered his auto "towards parked vehicles" before correcting himself and went through a red light, prosecutor Henry Fitch said. "Now I need to pay like a man".
"Only we need to try, that he understands, and how he understands that it was a mistake".
Pochettino said that Lloris has beaten himself up over his mistake but deserved a second chance.
Pochettino also insists he has no concerns about the form of Harry Kane, who has made a sluggish start to the season after his World Cup exertions.
"It's not that I want to justify him, it's only because the period during the season always change".
"He is going to do another scan to see how is the evolution of his injury", Pochettino told Sky Sports.
"We're working hard to come back strong and as quickly as possible".