Sport is reporting that the Red Devils are hopeful of getting the Spain worldwide to commit to a new long-term contract as they look to secure the future of the talented goalkeeper.
They tried to sign De Gea the next summer but failed to persuade United to let him go and instead turned their attention to Courtois, who joined them in a £35 million transfer last week.
The 27-year-old has been linked with a move back to his homeland for a number of years, with Real's quest to replace standout goalkeeper Iker Casillas having rumbled on since his departure from the club three years ago.
That clears the way for de Gea to commit his future to United by formalising a new contract in the next few weeks.
With the path now clear, United hope that the task to keep De Gea has become that much easier.
De Gea's contract technically expires at the end of the current campaign but the club has an option to extend his deal until 2020.
Following a shaky start to his United career after joining from Atletico Madrid seven years ago, De Gea has since established himself as one of the best keepers in the world.
He is the only United player to win Sir Matt Busby Player of the Year award - which was first introduced in 1988 - on four occasions.