She hit 17 of her 22 shots from the field, made all but one of her attempts from three, and sank 15 of her 16 free throw attempts, putting up more than half of Dallas' points in a 104-87 win over NY.
"It's pretty big", Cambage said in an interview with Fox Sports.
"I have had big numbers in China and big numbers in Australia over the summer", Cambage said.
Cambage netted 53 points and had 10 rebounds and five blocks in the victory at College Park Center on the University of Texas at Arlington campus. She also made 4-for-5 shots from 3-point range and 15-of-16 free throw attempts.
However, in order to make a deal possible the FFA would have to top up any salary offered to Bolt from its $3 million fund to attract "marquee" players.
Cambage had previous stints in the WNBA, suiting up for the Tulsa World in both 2011 and 2013.
With 44 seconds remaining, the Australian hit a three from the top of the key to surpass the record. Dallas improved to 13-9 on the season and sit in fourth place now.
The only other player to score more than 45 points in a WNBA game was Moore of the Lynx, putting up 48 points in a double-overtime game in 2014. Working efficiently from the field, the 26-year-old shot 17-for-22 (73 percent).
Cambage returned to the Dallas franchise after sitting out the past four years.
Kia Nurse scored 25 points, with four 3-pointers, for NY (7-15), which saw its two-game winning streak snapped. Coming into Tuesday's tilt, Cambage was averaging 19.9 points-per-game.
When asked about matching up with Dallas and Cambage, Washington all-star guard Elena Delle Donne said, "Well, first of all, I hope she got out all her makes in that last game, hoping she doesn't drop 53 again".
Remarkable. One of the best post players this season, bar none. I don't think ESPN will overlook Liz Cambage anymore any time soon.