The government of Prime Minister Theresa May overcame a new rebellion in her government's ranks by defeating, by only 307 votes against to 301 in favour, a largely Conservative amendment to remain in the customs union, which would have destabilized its negotiating leverage with Brussels.
Later, the government was also left embarrassed when it abandoned plans to send MPs on an early summer break, amid ever-deepening divisions among Conservatives on Brexit.
The ex-foreign minister said he was unable to support the Chequers plan and is happy to be speaking out against it.
May's plan for Brexit - outlined in a white paper released to MPs in the House of Commons last week - has divided the already split Tory party.
Boris Johnson delivered a speech on Wednesday afternoon in the House of Commons claiming that it was "not too late" to save Brexit.
The 1990 Howe speech is widely credited with being one of the key events that brought down Prime Minister Margaret Thatcher.
The former London mayor, who has made his ambition to be prime minister clear in the past, told parliament he backed May but then savaged her Brexit policy saying it would leave Britain in a "miserable, permanent limbo".
Mr Johnson said the question of the Irish border, "which had hitherto been assumed on all sides to be readily soluble" had been allowed "to become so politically charged as to dominate the debate".
Dr Lee, who has joined the ranks of Tory Remainer rebels since quitting the government last month in protest at Mrs May's Brexit strategy, described Monday's events as "the worst experience I've had in politics in eight years".
But he insisted: "It is not too late to save Brexit".
"It would also be harder to get the medicines we need when we need them - this is particularly worrying for time-critical drugs and equipment", he said, giving the example of the Manchester Arena bombing in 2017, when some of the trauma treatments used for victims were initially stocked in Amsterdam.
Jacob Rees-Mogg, leader of the influential European Research Group of Tories and a potential rival to Mr Johnson in any future contest for the party leadership, hailed the Commons statement as "the speech of a statesman".
"We have consistently voted to protect people's jobs, wages and standard of living by maintaining our place in the single market and the customs union, but if making it happen requires entering into an all-party government, so be it".
Mr. Johnsons partisans know that recent polling shows that Britons dont believe that Mrs.
A Conservative MP has turned on his Prime Minister - Conservative leader Theresa May, submitting a "no confidence" letter.