"After five years of first-round losses here, I think I've grown a lot to get to the semi-finals".
"It will be an interesting semi-finals".
All four semi-finalists are aged 30 or over - the first time in the Open era that the men's singles semis at a Grand Slam have been contested exclusively by players over 30.
"There is no one other match in the history of tennis that has been played more than our match. Anything could happen", Nadal said.
The pair have produced some of the greatest matches ever seen - which include memorable Grand Slam finals and career-defining victories.
Champion in 2008 and 2010, Nadal will face off with Djokovic for a record 52nd time on Friday after the Serb earlier ended Kei Nishikori's campaign with a controversy-laden 6-3 3-6 6-2 6-2 triumph over the Asian ace.
"I play Los Cabos in Mexico - the beach", he smiled. It is always a big test. I think confidence is back for him. So far the four matches have been really, really good for me'. I tried to resist, maintaining focus.
In a match that delivered quality throughout, Nadal recovered from two sets to one down to treat the Wimbledon crowd to a match few will forget.
At five hours and 53 minutes, it was the longest final ever at a Slam.
While the Federer exit, to South African Kevin Anderson, losing 13-11 in the final set, is what will sadden most viewers and grab what there are of tennis headlines today, Nadal coming from two sets to one down against perennial almost man Juan Martin Del Potro produced perhaps the most awesome tennis of the day, and definitely the moment of the tournament.
A courageous effort from Isner but it is Anderson who will reach the final.
Opportunity knocks for both men here with a chance at a first Wimbledon final.
The South African is through to the last eight for the first time, and he said: 'Playing somebody like Roger Federer is going to be a great experience.
"I said at the beginning of the tournament, getting through to the quarters was a big goal of mine", he said. "That's all I got for you right now".
Asked if Djokovic can beat the Spaniard, Nishikori said: 'Yeah, for me he was playing very deep.
"With how I'm feeling physically and mentally, I'm in a very good spot".
"I just kept on telling myself I have to continue believing".