Seventeen months ago, Williams won her last major, the 2017 Australian Open, while pregnant.
Kerber, the former world No.1 and runner-up to Williams in 2016, plays Latvia's 2017 French Open champion Jelena Ostapenko in Thursday's second semi-final after outclassing Russian 14th seed Daria Kasatkina 6-3 7-5.
The match that precedes Williams on Centre Court promises to be more competitive. "She (Ostapenko) won a Grand Slam, as well". Her loss marks the first time in the Open era that any major has featured a quarterfinal round without a top-10 seed on either the men's or women's side, according to ESPN Stats & Information.
Nine-time Wimbledon champion and BBC pundit Martina Navratilova said: "She's been healthy here, hitting the ball hard and the seas have parted for her".
On the match, Williams produced five aces (to Goerges' three) and just seven unforced errors (to Goerges' 11).
As any great does, Williams took her game to another level, adjusted to Goerges' serve, and began to dominate with strong, well-placed returns.
Williams dropped her first set at this tournament as the 52nd-ranked Giorgi produced an impressive display of power and accuracy in the opener. Commenting on the matter before the championships commenced, Martina Navratilova said: "Forget the rankings; Serena is a contender for the title".
She probably should have done her homework on Williams, who crushed the upset-minded Italian after dropping the first set.
Kerber is bidding to become the first German woman to win Wimbledon was Steffi Graf in 1996.
Giorgi appeared a bit salty - maybe that's her normal demeanor - as she shook hands with Williams at the net after the match and quickly grabbed her bag and walked off the court.
Ostapenko's winning streak is intimidating, but Kerber can feel confident after refining her own game.
"I think the serve, it's one of the points I have more - I mean, I can't complain about my serve", Giorgi said.
"I feel good, I felt like I did better today, I had to, but this is only my fourth tournament back so I don't feel any pressure and have to win this", she said.
"It was a very tough match but I was just trying to enjoy it".
"I just want to be more of that role model for my daughter, for lots of people out there that just want to be inspired".
With no top-10 seeds making the quarterfinals for the first time in Wimbledon history, 11th-seeded Kerber is the highest-ranked player left in the hunt for the Venus Rosewater Dish.
Goerges had to do it the hard way after coming from a set down against the Dutch No.20 seed to win 3-6 7-5 6-1 and set up a showdown with the formidable Serena Williams. Williams hasn't lost a set against Goerges in three previous matches, including a victory last month at the French Open (6-3, 6-4) in the round of 32. Serving to stay in the match, Goerges lost the game in four short points, ending her Wimbledon run with a lob shot that flew long.
After claiming a 19th consecutive match win at the tournament she won in 2015 and 2016 but missed past year, she said she still had a way to go to regain her top level.
Jerry Bembry is a senior writer at The Undefeated.