"We only started to compete after 2-0 down, we scored, but of course over 90 minutes Manchester City were better", Pochettino said.
City still need 6 points to wrap up the title and will be desperate for a win against the Lilywhites to boost their confidence and morale and look to finish the season on a high.
Regardless of United's results, City will be crowned champions by beating Swansea next week.
Gabriel Jesus raced in behind an unsettled Spurs defence to drill home the opener on 22 minutes and Ilkay Gundogan slotted home the second from the penalty spot three minutes later as Hugo Lloris wiped out Raheem Sterling, although replays suggested the contact took place outside the area. The decision allowed Gundogan to step up and send Lloris diving the wrong way, pushing City into a 2-0 lead in the 25th minute.
City will clinch a third Premier League crown since 2012 if United fails to beat West Bromwich Albion or loses to Bournemouth on Thursday.
Pep reverted to a more defensive setup in the second half with the lead in hand, bringing on Nicolas Otamendi for Leroy Sane and resetting his fullbacks to standard positioning. Exclaimed manager Jurgen Klopp on hearing Salah is the first Liverpool player since Ian Rush 31 years ago to score 40 in a season.
"Myself and the players are disappointed the way we conceded goals but there is nothing to worry, we have to try and be ready to compete on Tuesday".
It's fair to say the Liverpool man did not take kindly to the news that the Premier League had eventually added the goal to Kane's tally.
Mohamed Salah has set his sights on breaking the Premier League record for most goals in a single season, Soccerway reports.
After just ten minutes of play, Spurs confidence had grown as they gave City a fight with ball possession, and by then, they had reduced the Citizen's dominance in the game to 68%.
The Dane has played an important role in Spurs' top-four challenge this season.
The Blues went looking for the third goal that would surely end the contest and the superb David Silva saw a low drive beaten away, but despite one or two half-chances, Spurs hung on.
To make matters worse for Saints, Huddersfield and Crystal Palace secured vital wins later in the day to leave Southampton five points adrift of safety with just five games left to save themselves.
They are already all-but assured of Champions League qualification for 2018-19, but still have work to do in order to get over the line.