The 29th Arab summit got underway in Saudi Arabia on Sunday under the patronage of Custodian of the Two Holy Mosques King Salman bin Abdulaziz, who warned of Iran's looming threat against the region.
The interference of several countries, namely Iran and Turkey, in the internal affairs of some Arab countries is among those items.
Discussions during the summit will shed light on the crisis in Syria following a tripartite strike by the US, France and the United Kingdom on several military and research targets in Syria.
King Salman announced a $150 million donation for the maintenance of Islamic heritage in East Jerusalem.
The heads of state of Arab League will discuss the civil wars in Syria and Yemen.
According to an official AL announcement released by Saudi Press Agency after the summit, decades-long Palestinian-Israeli conflict is the "core issue" concerned by the entire Arab world, which firmly insists the fact that East Jerusalem is the capital of the State of Palestine.
The Arab leaders participating in the summit have affirmed centrality of the Palestinian issue and importance of the status of eastern Jerusalem as the capital of the future state of Palestine.
Participants will condemn Iran's continued interference in the internal Arab affairs during the summit that is taking place in the eastern province of Dhahran of Saudi Arabia, and will urge Iran to exhibit a good neighbourly policy and refrain from using force or threatening to use force against neighbours.
"The Palestinian cause is our primary cause and it will remain so until our fraternal Palestinian people obtain all of their legitimate rights, starting with the establishment of an independent state, whose capital is east Jerusalem", he stressed.
Instead the king focused on rivalries with longtime foe Iran - only 160 kilometers (100 miles) across the Gulf from Dhahran.
The two regional titans, locked in proxy wars in Syria and in Saudi Arabia's southern neighbour Yemen, back opposing parties in Iraq and Lebanon.
"We urge the worldwide community to sanction Iran and forbid it to back Houthi terrorists and provide them missiles", the statement said.
Saudi Arabia will use the summit to seek Arab support to pile the pressure on Iran.
In February, Russia vetoed a Security Council resolution that would have expressed concern over Iran's failure to block supplies of missiles to Yemen's Houthis.
The summit also agreed on the necessity to secure the Arab World from the dangers terrorism poses and to work on combating terrorism and supporting all security, economic, social, cultural and intellectual means to preserve the Arab World's national security.
The Arab League was founded in 1945 to protect newly-won independence throughout the region.