However, they but failed to go past De Gea in goal.
Mourinho was also irritated at the focus on the absence of Pogba from his starting line-up.
"I think the only moment where we felt relieved was in the last couple of minutes in the first half where (we had) a couple of mistakes in possession and they had a couple of good situations with two David great saves", Mourinho said.
Manchester United legend Ferdinand, watching the last-16 clash in the BT Sport studio, was nearly in disbelief at De Gea's latest effort.
Pogba did eventually came on in the first-half in Spain because of an injury to Ander Herrera, but contributed little, making just one tackle and taking a solitary shot on goal.
"If I was one of you [the media] I would ask if the Manchester United manager agrees that Scott McTominay had a fantastic performance".
Mourinho added: "He looked fit and the way he was playing during the time he was on the pitch - he was pressing a lot, really high - you only do that when you feel good". I say it is not good, it is not bad.
Mourinho summed it up himself after the game, remarking: "I'm not happy, I'm not unhappy".
However, the 28-year-old's night didn't last long as Herrera went down clutching his leg in the 17th minute after attempting a routine back-heel in the Sevilla penalty area.
The manager took issue with the discussion surrounding the France global and instead extolled the virtues of Scott McTominay, but he added Pogba made a "big effort" to meet the requirements he placed on the team.
So with the draw, United have drawn 22 matches in the Champions League goalless, a record they share with AC Milan.
"I think all round he is the full package".
United will need to play the second leg on March 13 on the front foot, and if they do so, it should give the midfielder more opportunity to shine.