However, the Argentine - who will start in attack in the absence of injured forward Gabriel Jesus - is yet to find the net in five league visits to Anfield.
The contest looked to be over, with Liverpool's quickfire attack too much for a shellshocked City side. Liverpool were already losing that game when Sadio Mané was sent off but their subsequent collapse crystallised the idea of this team as defensively flaky free-wheelers, City as a kind of surging, pirouetting goal machine.
And they have shored up their suspect defence by paying an eye-watering £75 million ($102 million, 84 million euros) to Southampton for defender Virgil Van Dijk.
"To be fair it is still unusual, I think we still have to realise he has gone", he said. He was quite impressive, it was a really good game.
Liverpool are now sitting on a huge transfer kitty following the sale of Coutinho to Barcelona, so reinvesting that in a keeper like Kasper Schmeichel, Jack Butland or Jan Oblak would surely be sensible decision.
Vincent Kompany will likely remain sidelined for the trip to Anfield. City have lost 14 of their 20 meetings at Liverpool during the modern top-flight era, snatching their sole victory with a 2-1 win in May 2003 - when current City winger Leroy Sane was just seven years old. However, Antonio Conte have drawn their last three games in all competitions, including drawing 0-0 with Arsenal in their last outing in the EFL Cup semi-final first leg.
Never renowned for his prowess in front of goal, the 24-year-old England global left Arsene Wenger's side having registered nine goals across 132 league outings, but he never produced more than two in a single season which he managed in three separate campaigns (2011/12, 2013/14 and 2016/17).
Ahead of the match, Liverpool boss Jurgen Klopp said that he wouldn't replace Coutinho just for the sake of spending money.
This has the makings of a mouth-watering clash, as arguably the two most in-form teams are pitted against each other at Anfield. "He is training completely normal, and of course that is good for us".
City can never be counted out, however, and their sheer quality will be a real threat to the Reds.
Three quick thoughts on Liverpool's 4-3 Premier League win over Manchester City at Anfield on Sunday.
Beating Liverpool will be no easy feat, however: the Reds have been sensational this season, and they've scored a lot of goals.