Philippe Coutinho's €160m transfer from Liverpool to Barcelona at the weekend will have only served to reinforce the view that, if Tottenham were ever to consider selling Kane, the England forward would command a fee closer to that paid for Neymar than Coutinho.
The 1-1 draw against the Hammers put an end to a run of three consecutive league wins for Spurs, who sit in the fifth spot with 41 points.
A tempestuous night at Anfield witnessed a more progressive display from Everton than they offered during their visit in December, but it proved insufficient as a late goal burst their cup dreams for another year.
With Yannick Bolasie back in good health and a potential deal to bring Theo Walcott into the club alongside new striker Tosun, Big Sam needs his new look attack to deliver if his relative success is to continue at Everton.
It's been over five years since Everton last tasted victory over Tottenham home or away, and it's hard to see that barren run ending this weekend. He was on loan from Atletico Madrid with Spurs eventually signing him on a permanent.
Kane is among the players on Real Madrid's list of targets for next season.
Real are the club who would appear to hold the all the aces in any pursuit of Kane, however. He's still very much a fan favorite amongst Spurs fans and is sure to receive a very warm welcome by the Tottenham faithful when the teams take the field at Wembley on Saturday.
Spurs are huge favourites to win, and they are available at their best odds of 2/7 at BetVictor.
Spurs manager Mauricio Pochettino has been asked about Kane's future several times this season.
The duo have had some enthralling meetings down the years and the clash in the capital could prove to be yet another tasty affair between the Premier League sides.