Momentum for a possible Winfrey presidential run sparked after the former TV host delivered a moving speech while accepting the Cecil B. DeMille Award at the Golden Globes on Sunday, one that many fans on Twitter couldn't help but note sounded similar to a campaign speech.
But if Winfrey is smart - and she is - she will wonder whether the message she tried to convey will get lost in all the political chatter.
Winfrey said: "What I know for sure is that speaking your truth is the most powerful tool we all have..." I urge all of us to not only support survivors and bystanders who are fearless enough to tell their truth, but to promote restorative justice.
"I think we need a mindful, empathetic human being in the White House who understands people and puts people ahead of their own ideas of power and self-aggrandizement - and I think Oprah has already proved her capacity for selflessness", he said. "She's not thinking that, 'Oh, since I did this speech, I qualify to be president or I even want to be president'".
In an Instagram post by Erica Campbell, who is one of of the Gospel singing Mary Mary duo, shared her thoughts on Winfrey's Golden Globes speech, stating that Winfrey has successfully motivated and inspired her. "I thought they'd be talking about it because I knew it was going to be good". "But that would be something she would have to determine and lay out if she made a decision to run and what the campaign would look like". "I think it is something that Oprah would have to feel and sense for herself".
But others worry it's a continuation of the trend, personified by the current U.S. leader, that rejects intellectual depth and expertise should Ms Winfrey decide to run.
Actress Meryl Streep also endorsed Winfrey. "I don't think she had any intention, but now she doesn't have a choice".
"She's popular, she's brilliant, she's a wonderful woman", he said at the time.