The 17-foot, 1-inch python, weighing 132 pounds, is the longest ever brought in for the agency's Python Elimination Program.
According to the South Florida Water Management District (SFWMD) Governing Board, the Python Elimination Program compensates hunters like Leon and Crum for killing the "destructive" animals, which are now classified as an apex predator in the state.
"If that snake was alive right now, it would probably take like three of us to be able to control that snake", python hunter Jason Leon told NBC Miami.
He said in an SFWMD video that he grabbed the female snake while she was still submerged in water.
Leon says the Burmese python is causing serious problems for the Everglades.
The massive python was the biggest so far in the district hunt established as a way to to raise the profile of the spread of the invasive species.
'We have these guys out there eating our alligators, raccoons, possums, otters, pretty much everything out there, ' Leon said.
Since March, the program has eradicated more than 700 snakes in on District lands in Miami-Dade, Broward and Collier counties, which, if laid out end to end, would measure over 1.4 km and weigh over 4,500 kilos. The program pays $50 for for a four-foot snake and $25 for each additional foot beyond that. So in total, the snake was worth $375.