After being sworn in as the US President in January, Trump has hosted several top Asian leaders at the White House or his summer home in Mar-a-Lago, Florida.
During his trip from November 3 to 14, Trump will participate in a series of bilateral, multilateral and cultural engagements.
Among the leaders Trump could meet during his trip is Russian President Vladimir Putin who is also expected to attend the Asia Pacific Economic Cooperation forum in Dà Nang, Vietnam.
It will be Mr Trump's first visit to the region as president and comes as Kim Jong-un moves closer to his goal of having a nuclear-tipped missile that could strike the US.
The nuclear stand-off with North Korea has united the US and China despite far-reaching disagreements over trade.
The White House said Trump will also "emphasize the importance of fair and reciprocal economic ties with America's trade partners".
The US President has warned North Korea it would face total devastation if it threatens the United States - Mr Kim has in return blasted Mr Trump as "mentally deranged".
A U.S. official said Asian leaders who met Mr Trump at the United Nations General Assembly in NY last week helped persuade him to attend in unity with key Asian allies.
Trump's visit will "strengthen the worldwide resolve to confront the North Korean threat" and ensure the denuclearization of the Korean Peninsula, according to the USA administration.
Mr Trump's visit to China will reciprocate a trip to the United States made in April by Chinese President Xi Jinping.