Already trailing by a goal before the red card, Liverpool went in 2-0 down at the break and then struggled throughout the second period. It's half man of the match poll and half power ranking, and we want to use it to find out who you think played well after each Liverpool match and, at the other end, who you'd maybe like to see given the next game off.
Mignolet had to save with his feet in the 35th minute to keep out a low shot from John Stones after the ball fell to the City defender inside the box following a corner.
The complexion of the contest changed entirely after Sadio Mane was dismissed for striking City keeper Ederson in the head with a high boot and De Bruyne instantly made the host's numerical advantage count during a prolonged period of stoppage time, picking out Gabriel Jesus with a pinpoint cross.
Guardiola, whose side went top by a point over city rivals Manchester United who play Stoke later, said thankfully Ederson emerged relatively unscathed.
"I am not concerned in the long term", Klopp said. We also need to learn, the first half we need to influence the game in another direction.
As regards the general performance, Klopp said he was disappointed Liverpool didn't take their chances when it was 11 against 11, and lamented the amount of space his side gave up.
"I will try to ignore the result - not the mistakes but the result. Thank you for all the messages".
"I'm not satisfied with a point because we were the team closer to winning".
The risky incident ended up changing the entire complexion of the game, and the final scoreline of 5-0 marks the worst defeat for Jurgen Klopp, ever.
Jamie Vardy got one back for Leicester with a penalty and Conte said: "We must be delighted". They didn't create many things.
"If City takes too much confidence from this game today, they make a mistake", Klopp said.