Police evacuated some 120 residents on Wednesday from the facility, which the storm left without air conditioning.
"To my knowledge and to my understanding, what I have right now, there's a total of five deaths from the same facility", Sharief said. The building has been sealed off while police investigate. Police officials said other patients were in critical care.
Video from above the scene shows the buildings residents sitting on wheelchairs outside the nursing home. Families looking for information can call the hospital hotline at 954-265-1074.
More than 100 people were evacuated from the Rehabilitation Center, in Hollywood, on Wednesday morning where residents were suffering from intense heat and lack of power after the deadly hurricane.
Ten million people are still without power in Florida, Georgia and the Carolinas after Hurricane Irma.
Information from the Associated Press and WPLG-TV was used in this report. "We've been calling and calling".
Check back with NBC 6 for updates.