This isn't Samberg's first foray into sports mockumentaries: Back in 2015, he teamed up with HBO to roast professional tennis in 7 Days In Hell, a film that made an effort to show knowledge of the sport's history and culture.
HBO debuted the trailer for his latest spoof, "Tour de Pharmacy", which tells the story of five cyclists in 1985 in an era when almost every competitor dopes up for an advantage.
Watch the Tour De Pharmacy trailer below. Even disgraced cyclist Lance Armstrong will be in the special as a "anonymous informant".
This is just a teaser trailer, and a big chunk of it is spent touting all the names involved. Andy Samberg will star alongside Orlando Bloom, Daveed Diggs, John Cena, Dolph Lundgren, Phylicia Rashad, Freddie Highmore, Julia Ormond, Mike Tyson and many more actors who eager to get in on the fun.
In 1982, the sport's most venerable, time-honored race was marred by the doping of virtually all of its competitors. No, I don't know how they convinced him to participate either.
Called Tour de Pharmacy, the film has been created by Andy Samberg and Murray Miller and is directed by Jake Szymanski.
Tour de Pharmacy will air in the United States on HBO on July 8. Let's think... oh, right: Lance Armstrong. Riddled with nefarious characters, that year's competition was a hornet's nest of moral depravity.