This is the president's first worldwide trip, but Ivanka Trump made a brief trip to Germany in April to appear on a panel at a conference dedicated to helping women in business. These are not the best of circumstances.
Here are three things to watch on President Donald Trump's foreign trip.
During his time in Riyadh, Trump is expected to emphasize a shared commitment to fighting the Islamic State, al-Qaida and other terrorist networks - including those backed by Iran - and to back it up with a major new package of weapons sales for the Saudis.
This is said against the backdrop of the President's proposed travel bans against people from several Muslim-majority countries, which are now still mired in the courts. McMaster told reporters that, while in the Palestinian territories, Trump "will convey the eagerness to facilitate an agreement that ends the conflict and he will urge leaders to take steps that will help lead to peace". The Trump administration will have to waive more sanctions next month if it wants to stick by the nuclear deal.
Will it be the populist, "America first" president who declared to union workers on April 4 that he was "not president of the world?" The US says the programme is a breach of worldwide law because the missiles could carry nuclear warheads in the future.
Saudi leaders seek to convince President Donald Trump that his priorities are theirs, too, and that they are indispensable partners in fighting terrorism, in confronting Iran, in bolstering USA businesses and perhaps in pursuing peace between Israelis and Palestinians. In the past, Trump called the alliance "obsolete".
Trump's trip was always going to be dramatic.
He noted that Saudi Arabia severely restricts freedom of expression and religion, and do not allow the construction of Christian churches.
Addressing a press conference, the minister said Bangladesh would extend necessary support and troops, if requested, considering people's respect, love and devotion for the two mosques - Al-Masjid al-Haram (the Sacred Mosque) in Makkah and Al-Masjid an-Nabawi (the Prophet's Mosque) in Madina.
"Saudi Arabia is delighted", Henderson said.
"Until the oil went down, Saudi Arabia was making a billion dollars a day".
Ivanka Trump will travel with the president to Saudi Arabia, Israel and Italy on his upcoming foreign trip, a White House official said. The centerpiece of the president's visit to Brussels is now a tour of the new North Atlantic Treaty Organisation building, which will open in about a year.